个人介绍： |
刘丽教授主要从事食品营养糖组学、功能糖生物学及糖生物工程方面的研究，包括营养与糖生物学间的关系、寡/多糖的结构和生物功能研究、糖酶生物工程研究、糖生物技术等。 主要工作业绩如下： 以第一/通讯作者发表SCI论文30余篇。代表性论文如下： 1）Huang K., Parmeggiani F., Pallister E., Huang C.J., Liu F.F., Li Q., Birmingham W.R., Both P., Thomas B., Liu L., Flitsch S. (2018): Characterisation of a bacterial galactokinase with high activity and broad substrate tolerance for chemoenzymatic synthesis of 6‐aminogalactose‐1‐phosphate and analogues. ChemBioChem DOI: 10.1002/cbic.201700477 2）Wang M., Zhang X.Y., Guo R.R., Cai Z.P., Hu X.C., Chen H., Wei S., Liu L.† (2018): Cloning, purification and biochemical characterization of two β-N-acetylhexosaminidases from the mucin-degrading gut bacterium Akkermansia muciniphila. Carbohydrate Research 457: 1-8. 3）Awad F.N., Laborda P., Wang M., Lu A.M., Li Q., Cai Z.P., Liu L.† (2017): Discovery and biochemical characterization of a mannose Phosphorylase catalyzing the synthesis of novel β-1,3-Mannosides. Biochimica et Biophysica Acta DOI: 10.1016/j.bbagen.2017.09.013. 4）Chen H., Cao C., Kulinich A., Liu L.†, Jung Y.S.† (2017): Engineering of an episomal plasmid suitable for high-throughput expression in Pichia pastoris. Combinatorial Chemistry & High Throughput Screening 5）Li Q., Huang Y.Y., Conway L.P., He M., Wei S., Huang K., Duan X.C., Flitsch S.L. (2017): Discovery and Biochemical Characterization of a Thermostable Glucose-1-phosphate Nucleotidyltransferase from Thermodesulfatator indicus. Protein & Peptide Letters 6）Laborda P., Wang S.Y., Lu A.M., He M., Duan X.C., Qian J.Y., Jung S.Y., Liu L.† (2017): Diastereoselective One-step Synthesis of 2-Keto-3-deoxy-D-glycero-D-galacto-nononic acid (KDN) Analogues as Templates for the Development of Influenza Drugs. Advanced Synthesis & Catalysis 7）Wang S.Y., Laborda P., Lu A.M, Wang M., Duan X.C, Liu L.† (2017). Chemo-enzymatic approach to access diastereopure α-substituted GlcNAc derivatives. Journal of Carbohydrate Chemistry 8）Wang M., Wei S., Wang T., Liu L.* (2017). Gene cloning, expression, purification and characterization of a beta-N-acetylhexosaminidase from Solitalea Canadensis. Acta Microbiologica Sinica 9）Wang W.L., Du Y.M., Wang W., Conway L.P., Cai Z.P. and Liu L.† (2017): Comparison of the Bifidogenic Activity of Human and Bovine Milk N-glycome. Journal of Functional Foods 10）Lv Y.M., Laborda P., Huang K., Cai Z.P., Wang M., Lu A.M., Doherthy C., Liu L.†, Flitsch S.† (2017): Highly efficient and selective biocatalytic production of glucosamine from chitin. Green Chemistry 19, 527-535 |
